CFP and coinfection: However, Xpert MTB/RIF and Xpert MTB/RIF Ultra are not superior to Mtb culture for pediatric TB diagnosis [10, 30].Serum CFP-10pep also had similar sensitivity for all TB manifestations, including HIV/TB co-infection and extrapulmonary TB, in contrast to Xpert MTB/RIF which exhibits reduced sensitivity for these cases, although direct comparisons are still required to validate this difference.