The results showed that high levels of pentraxin-3 (> 569.088 ng/mL) during the acute phase were significantly associated with the death in HFRS patients, with a HR of 7.77 (2.29–26.35) in comparison with the low pentraxin-3 (< 569.088 ng/mL) (Fig. 4). This evidence concerns the gene PTX3 and hemorrhagic fever with renal syndrome.