The above findings indicate that pentraxin-3 can serve as an early predictor for the disease severity of HFRS, which chimes in with the results of pentraxin-3 in sepsis, acute pancreatitis, nephropathia epidemica and other diseases [9, 10, 12, 14, 16, 17]. The gene discussed is PTX3; the disease is acute pancreatitis.