FILIP1L and invasive carcinoma: Having confirmed that differential FILIP1L methylation and expression is also present in human cSCC, we evaluated its clinical relevance in humans using Infininium MethylationEPIC data provided by Hervás-Marín et al. for 10 low (initial invasive carcinoma) and 8 high-risk (high-risk non-metastatic carcinoma and metastatic carcinoma) samples [33].