Additionally, trout monoamine oxidase has been found to be equivalently effective to human monoamine oxidase in metabolizing 5-HT and PEA [68], making it unlikely that the increase in aggression is an off-target effect of using mammalian MAOA. Further characterization of anxiety levels following transfection, pharmacological rescue [90], and quantification of the downstream neurotransmitters remain as potential avenues to a better mechanistic understanding of this result. Here, MAOA is linked to Anxiety.