The α-cyano-4-hydroxycinnamic acid (CHC)-mediated block of cellular lactate import via monocarboxylate transporter 1 (MCT1) was shown by Sonveaux et al. to drive oxygenated tumor cells into aerobic glycolysis (Warburg effect) by using glucose instead of lactate as primary energy substrate. Here, SLC16A1 is linked to neoplasm.