The autosomal dominant familial periodic fever, best known as tumor necrosis factor (TNF) receptor-associated periodic syndrome (or TRAPS), initially named “familial Hibernian fever”, is the most prevalent dominantly inherited disease among inflammasomopathies, caused by monoallelic missense mutations in the TNFRSF1A gene encoding the 55kD receptor of TNF (TNFR) [18]. Here, TNF is linked to TNF receptor 1-associated periodic fever syndrome.