Consistent with this point, Oehme et al. [68,69] found that HDAC10 deletion acetylated Hsp70/heat shock cognate 70 (Hsc70), and impairs the autophagic flux by thwarting the blend between autophagosomes and lysosomes, which allows drug-resistant neuroblastoma cell to recover sensitivity to doxorubicin. Here, HDAC10 is linked to neuroblastoma.