BRD4 and Familial prostate cancer: Jin et al. [77] found that low expressed nuclear receptor co-repressor 2 (NCOR2)–HDAC10 complex is negatively associated with deubiquitinase ubiquitin-specific peptidase 17 like family member 2 (DUB3), which may interact with BRD4 and further inhibit sensitivity to BETi in prostate cancer cells and in vitro.