CIN23 is a gene signature derived from the human metastatic cell line models (MDA-MB-231) engineered to over-express MCAK (to suppress CIN) or a dominant negative version of MCAK (to increase CIN) (Bakhom, 2018, Cailleau et al., 1978). The gene discussed is KIF2C; the disease is cervical squamous intraepithelial neoplasia.