BMI: Body mass index, WHR: Waist–hip ratio, SGPT: Serum glutamate pyruvate transaminase, HOMA-IR: Homeostatic model assessment of insulin resistance, QUICKI: Quantitative insulin sensitivity check index, TES: Serum testosterone, PMP: Platelet microparticle, hsCRP: Highly sensitive C-reactive protein, IL-6: Interleukin 6, TNFα: Tumor necrosis factor alpha, Bivariate correlation was done to determine Pearson's correlation coefficient (r) between obesity parameters, insulin resistance markers, and serum testosterone with markers of chronic inflammation in group A. The gene discussed is TNF; the disease is obesity due to melanocortin 4 receptor deficiency.