Melanoma, non-small cell lung cancer, non-squamous cell lung cancer (with high PD-L1 expression), renal cell carcinoma, classic Hodgkin's lymphoma, gastric or gastroesophageal junction adenocarcinoma, urothelial carcinoma, cervical cancer, large B-cell lymphoma, Merkel cell carcinoma. The gene discussed is CD274; the disease is classic Hodgkin lymphoma.