PIK3CA and non-small cell lung carcinoma: In a study of 5125 Chinese NSCLC patients, 160 multiple genetic mutations were found including EGFR+PIK3CA, EGFR+KRAS, KRAS+PIK3CA, EGFR+BRAF, PIK3CA + BRAF, and EGFR+KRAS +PIK3CA [18].