In the subgroup of cancers, the serum ANG concentrations were significantly higher in patients who advanced colorectal cancer (CRC) (p = 0.004), acute myelogenous leukemia (AML) (p = 0.001), multiple myeloma (MM) (p < 0.001), myelodysplastic syndromes (MDSs) (p = 0.001), and heart failure (p < 0.001) than those in healthy individuals. This evidence concerns the gene ANG and colorectal cancer.