CXCL10 and myocardial ischemia: Of the ELR-negative CXC chemokines, interferon-inducible protein (IP)-10/CXCL10 peaks in the early reperfusion phase and regulates the cellular composition attenuating adverse remodeling, since IP-10 deficiency resulted in a hypercellular early reparative response with intense infiltration of myofibroblasts suggesting the exertion of anti-fibrotic actions following myocardial ischemia (92).