FGF21 and diabetes mellitus: In this cross-sectional study of a diabetes-enriched multiethnic cohort in Singapore consisting of Chinese, Malays, and Indians, we assessed whether sex modulates the relationship between FGF21 and subclinical carotid atherosclerosis and explored interactions with other traditional cardiovascular risk factors, with the aim of enhancing our understanding of FGF21 in the atherosclerotic pathways.