ADAMTS12 and asthma: ADAMTS-12 also participates in other pathological situations in which a common trail of an inflammatory outburst is present such as the allergen-induced hyperresponsiveness detected in asthma or the extracellular matrix degradation observed in osteoarthritic processes (Liu, 2009; Moncada-Pazos et al., 2012; Nah et al., 2012; Paulissen et al., 2012).