Two hundred CRC patients in the GSE39582 cohort were categorized into high/low-expression groups according to the median expression values of each hub gene, then the correlations between the six hub gene expressions and OS were assessed by log-rank test; the results revealed that higher expressions of CALD1 and COL1A2 were associated with poorer OS (log-rank P = 0.012 and 0.044, respectively) (Figure 5). Here, CALD1 is linked to colorectal carcinoma.