Regarding sex, age, hypertension, BMI, smoking habits, ALT, AST, γ-GT, ALP, serum albumin, serum bilirubin, PT, APTT, serum creatinine, serum triglyceride, fibrinogen levels, serum CRP, HOMA-IR, protein C, protein S, Antithrombin III, Factor VIII, PAI-1, serum homocysteine, D-dimer, ANA, ACA-IgG, and anti-dsDNA, the difference was not significant between the two groups (all P > 0.05). The gene discussed is SERPINE1; the disease is hypertensive disorder.