Three human myeloid-related leukemia cell lines (one of chronic myeloid leukemia origin: K562; two from acute promyelocytic leukemia: HL60 and NB4) were depleted for the long isoform of PHF19 using two different short hairpin RNAs (shRNA) (Figure 1A, inner panels). This evidence concerns the gene PHF19 and chronic myelogenous leukemia, BCR-ABL1 positive.