NFKB1 and central nervous system cancer: Subsequent analyses showed that the upregulated genes in TERTmut gliomas were enriched in various immune-related pathways including cell division, interferon-gamma-mediated signaling pathway, NF-κB signaling pathway, positive regulation of NF-κB signaling, inflammatory response, innate immune response, immune response, and antigen processing and presentation (Figure 2A).