ABCA1 and atherosclerosis: As circDENND1B harbors eight binding sites for miR-17-5p, and miR-17-5p has been reported to modulate the progress of atherosclerosis via Abca1 (He et al., 2015; Tan et al., 2019; Liu L. et al., 2020) (Figure 5D), we investigated the relationship between circDENND1B and miR-17-5p.