ANKRD11 and KBG syndrome: The entry point for this study was the association of the chromatin regulator ANKRD11 (Ankyrin Repeat Domain 11; previously named ANCO-1) with KBG syndrome (OMIM #148050), a rare, autosomal dominant, congenital disorder characterized by a distinct craniofacial gestalt (Morel Swols and Tekin, 2018).