Uncoordinated 5 netrin receptor B antisense RNA 1 is highly expressed in ovarian cancer, and a recent study has shown that its knockdown activates caspase 3 in ES2 and SKOV3 cells, suggesting the apoptosis-suppressive role of UNC5B-AS1 (Wang et al., 2020). The gene discussed is UNC5B; the disease is ovarian cancer.