Several genes were shown to be associated with AL and AL/CRC; however, previous studies did not report associations between TGFBR1 and AL or AL/CRC (Cheng et al., 2013; Miyake et al., 2015; Li et al., 2020; Lin et al., 2020; Tang et al., 2020). Here, TGFBR1 is linked to colorectal carcinoma.