TGFBR1 and colorectal carcinoma: First, the rs10760673 SNP of TGFBR1 was significantly associated with the progression of myopia (OR = 1.536, P = 0.008) and increases in AL and AL/CRC (β = 0.03, P = 0.011; β = 0.003, P = 0.032, respectively).