However, paradoxically, a higher expression of CD70 in DLBCL is associated with an unfavorable prognosis, and constitutive expression of CD70 has also been described in other types of lymphomas including Hodgkin's lymphoma and mantle cell lymphoma, as well as solid tumors such as clear cell, ovarian, and nasopharyngeal carcinomas (70). The gene discussed is CD70; the disease is diffuse large B-cell lymphoma.