CCNB1 and malignant colon neoplasm: In particular, CCNB1 was significantly correlated with patient survival in all three datasets (P = 0.003 in TCGA, Figure 6A; P = 0.004 in GSE39582, Figure 6B; P = 0.050 in GSE41258, Figure 6C), indicating that CCNB1 might be the most important cyclin gene for the prognosis of colon cancer.