The GASC score was positively correlated with PD-1, PD-L1, PD-L2, TL1A, TIM3, Galactin-9, CTLA-4, CD80, CD86, CD155, LAG3, and CIITA in all glioma population and the HGG population (Figure 9). The gene discussed is CTLA4; the disease is central nervous system cancer.