Although tremendous efforts have been made to investigate DGE, and many factors, such as inflammation, postoperative hyperglycemia, ischemia, gastric atony, motilin levels, and type of surgical procedure, have been proposed to be related to DGE, the exact pathogenesis of DGE still remains unclear, and the prevention and treatment strategy for DGE has not been established yet. Here, MLN is linked to ischemia.