Ursolic acid, a triterpene presents in Prunella vulgaris L and Ilex rotunda Thunb, represses T24 bladder cancer cell growth by regulating anti-apoptotic NF-κB-p65 and AKT signaling, and suppressing IκBα, NF-κB-p65, and AKT phosphorylation. This evidence concerns the gene AKT1 and urinary bladder carcinoma.