Nineteen coding variants located in 10 cancer-related genes (ACVR2A, PCLO, TBCK, ADGRV1, COL1A1, GABBR1, MUC16, MAGEC1, FASLG, and JAK1) were identified in 96.7% of patients (87/90). The gene discussed is ACVR2A; the disease is cancer.