Abbreviations: APACHE, Acute Physiological and Chronic Health Evaluation; BMI, body mass index; CRP, C-reactive protein; hs-cTnT, high-sensitivity cardiac troponin T; SOFA, Sequential Organ Failure Assessment; WBC, white blood cell; IQR, interquartile range; COPD, chronic obstructive pulmonary disease. The gene discussed is TNNT2; the disease is chronic obstructive pulmonary disease.