Insulin pens alleviate some of these worries, as well as overcome dosage issues that exist with vials and syringes;9 however this method is itself not error free.10 A shift towards oral delivery of insulin has the potential to improve the uptake of insulin therapy and revolutionize diabetes care since it is a noninvasive therapeutic approach without the side effects caused by frequent subcutaneous (S.C.)injection.11–14. The gene discussed is INS; the disease is diabetes mellitus.