However, since lipid-lowering abilities of A. Graveolens L. extract and dill tablets through down-regulation of HMG-CoA reductase gene and inhibition of its activity were observed in our previous study (10), we hypothesized that dill tablets may exhibit a beneficial effect on the HCD-induced AD model by lowering serum cholesterol and attenuating unpleasant aspects of hypercholesterolemia, including alleviation of Aβ deposits and enhancing learning and memory abilities. Here, HMGCR is linked to Alzheimer disease.