MYOCD and neoplasm: In contrast, while 3 of 6 sites (50%) of 500 inoculum and 2 of 6 sites (33%) of 50 inoculum in cohort of DOX treatment (knockdown of MYOCD expression) developed tumor, control-diet fed cohort developed at a significantly lower incidence (1 of 6 sites (17%) and 0 of 6 sites respectively) (Figure 2F).