Consistent with its effect on tumor growth, hEND-CD3/BiTE also significantly improved mouse survival (mean survival time, 100 days; P < 0.05) compared with the PBS (mean survival time, 37 d), hEND-CD3/BiTE alone (mean survival time, 36 d), PBMCs alone (mean survival time, 40 d), and hENDM-CD3/ BiTE+PBMCs (mean survival time, 42 d) groups. The gene discussed is CEP70; the disease is neoplasm.