For example, Wang et al. 39 reported new tumor blood vessel-targeting nanoparticles, vincristine-loaded and F56-peptide conjugated nanoparticles (named F56-VCR-NPs); the F56 peptide has high affinity and specific VEGFR-1 binding ability and can achieve a high degree of cell internalization. Here, FLT1 is linked to neoplasm.