When comparing AG PCa to the combined group of low risk PCa and non-PCa, biomarkers with significant differences included B7-H3 (p<0.05), %fPSA (p<0.05, lower in AG), GDF-15 (p<0.01), Fuc-PSA (p<0.001), and PSA and phi (both at p<0.0001). The gene discussed is GDF15; the disease is posterior cortical atrophy.