In Table 2, to detect AG PCa from low risk PCa at a fixed sensitivity of 95.0%, the specificity of the four-marker panel of phi, Fuc-PSA, SDC1, and GDF-15, and the combination of phi and Fuc-PSA both had a specificity of 76.0% in comparison to that of 56.0% for phi (p=0.029, and 0.013, respectively) and 44.0% for PSA alone. The gene discussed is SDC1; the disease is posterior cortical atrophy.