A logistic regression model was constructed to evaluate the ability of Fuc-PSA to further improve performance of phi. We then identified other contributing factors including SDC1, GDF-15, and/or Tie-2, and further evaluated the diagnostic performance of serum biomarker combinations in separating AG from low risk PCa only or low risk PCa and non-PCa cases. The gene discussed is GDF15; the disease is posterior cortical atrophy.