NFATC3 was widely associated with the progression and prognosis of multiple human cancers, such as colorectal cancer (CRC) 44, gastrointestinal cancer 45, human glioblastoma (hGB) 46, oral/oropharyngeal squamous cell carcinoma (OSCC) 47 and breast cancer 48. The gene discussed is NFATC3; the disease is glioblastoma.