Analysis of the GSE14520 dataset for SOX4 expression at various BCLC stages revealed significantly elevated expression in each BCLC stage P <0.001, Figure 9A), but least expressed in the BCLC stage C. Next, we combined BCLC stage 0 and A to constitute the early-stage cancer category and BCLC stage B and C to constitute the advanced-stage cancer category. The gene discussed is SOX4; the disease is cancer.