We observed comparatively low counts of CD45 pan-leukocyte marker (MGMT unmethylated tumour core mean normalised value (MGMTuc) = 7.93 [0.83], MGMT methylated tumour core mean normalised value (MGMTmc) = 9.19 [1.00]), and CD45RO isoform (MGMTuc = 7.48 [0.50] and MGMTmc = 8.29 [0.81]) which is in keeping with low immune infiltration irrespective of MGMT methylation status within IDH-wild-type GBM. This evidence concerns the gene PTPRC and neoplasm.