The checkpoint molecule B7-H3 (CD276) is statistically increased in MGMT methylated tumour cores compared with unmethylated tumour cores of GBMs (p = 0.023); MGMT methylated tumour core counts: 14.07 [1.02] compared to MGMT unmethylated GBM (tumour core: 12.35 [0.87]). Here, CD276 is linked to neoplasm.