MAP3K2 and central nervous system cancer: Recently, four groups reported different circPITX1-mediated ceRNETs in glioma cells, i.e., circPITX1/miR-518a-5p/IL17RD (Zhan et al., 2019), circPITX1/miR-1304/ERBB4 (Chen M. et al., 2020), circPITX1/miR-379-5p/mitogen-activated protein kinase 2 (MAP3K2) (Lv et al., 2019), and circPITX1/miR-329-3p/NIMA-related kinase 2 (NEK2) (Guan et al., 2020).