In 2020, four groups reported novel XIST-mediated ceRNETs that promote glioma progression, i.e., XIST/miR-133a/SOX4 (Luo et al., 2020), XIST/miR-126/IRS1 (Cheng et al., 2020), XIST/miR-204-5p/Bcl-2 (Shen et al., 2020), and XIST/miR-329-3p/CREB1 (Wang Y.P. et al., 2020). The gene discussed is XIST; the disease is central nervous system cancer.