TGFB1 and pemphigus foliaceus: Specific depletion of DCs by diphtheria toxin (DT) in a mouse strain expressing zinc-finger and BTB domain containing 46 (Zbtb46; transcription factor keeping DCs in a quiescent state)-DT receptors was found to result in severe PF in a TGF-β1-induced mouse model of PF (167).