However, genes that are associated with NK cell activation (e.g., SH2D1B and KLRF1) and inhibition (e.g., KIR2DL3 and KIR3DL2) were both reduced, suggesting the complex role of NK cells in the pathogenesis of VKH diseases. This evidence concerns the gene KIR2DL3 and Vogt-Koyanagi-Harada disease.