This results in the release of inflammatory cytokines and growth factors, including IL-1β, TNF-α, IL-17A, IL-17F, IL-6, vascular endothelial growth factor (VEGF), and angiopoietin-1 (ANG1) (10), which promote angiogenesis during the pathogenesis of psoriasis (11, 12). This evidence concerns the gene TNF and psoriasis.