CD8A and graft versus host disease: Based on histopathological features, immunohistochemistry and clinical data, various GvHD-like changes were observed in the skin: parakeratosis, dyskeratosis, intensive basal layer destruction, intracellular oedema, subepidermal atypic lymphocyte T infiltration without features of malignancy (CD3+, CD4+>CD8+ at a ratio of 1.5-2:0, incidental CD30+), and focal destruction of skin appendages (Figure 3A) despite the lack of HSCT or organ transplantation in the patient’s past medical history.