It should be mentioned that an effective cure for HIV-1 infection has been reported in two patients by CCR5Δ32/Δ32-hematopoietic stem cells (HSCs) transplantation, observing that latently infected cells were eliminated and replaced with HIV-1 resistant donor CCR5–/– cells (Hütter et al., 2009; Gupta et al., 2019). The gene discussed is CCR5; the disease is HIV-1 infection.