LAMA2, MLL4 and PLXDC2 are specifically expressed in (pre-)diabetic sera; CD99 is expressed in the sera of both healthy and (pre-)diabetic patients; and CD14, CLU and SAA2 are expressed in the sera of healthy, (pre-)diabetic and stroke subjects (Figure 4 and Supplementary Figure 3) (41). Here, CLU is linked to stroke disorder.