PPARG and cancer: Also in this case while the latter compounds can play pathophysiological role in cancer progression by promoting angiogenesis (Johnson et al., 2015), the former compounds have been reported to be endowed of significant anti-inflammatory activities, mediated by the inhibition of NF-kB, and the increase of peroxisome proliferator-activated receptor-gamma (PPAR-γ) transcription activity (Norwood et al., 2010).