MTOR and Hypertension: Data from our study showed that EMPA could ameliorate SNT-induced hypertension and left ventricular dysfunction in mice, and alleviate SNT-induced H9c2 cardiomyocyte viability loss via regulation of adenosine 5’-monophosphate–activated protein kinase–mammalian target of rapamycin (AMPK-mTOR) signaling–mediated autophagy.