Postoperatively, routine aspirin, P2Y12, and UFH were recommended for the prevention of venous thromboembolism in patients requiring prolonged bed rest, at the same time, isosorbide nitrate sustained-release capsule were used to dilate coronary arteries, atorvastatin calcium tablets were used to stabilize plaques. This evidence concerns the gene P2RY12 and venous thromboembolism.