Then, we investigated in a similar setting potential effects of two variants previously implicated in PD etiology (Campêlo and Silva, 2017) and increasing the expression levels of SNCA gene, namely rs356219 (Fuchs et al., 2008; Pihlstrøm et al., 2018; Luo et al., 2019) and D4S3481 (Chiba-Falek et al., 2005; Fuchs et al., 2008; Trotta et al., 2012). This evidence concerns the gene SNCA and Parkinson disease.